EDN1, endothelin 1, 1906

N. diseases: 679; N. variants: 23
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.050 AlteredExpression disease BEFREE For this purpose, we immunohistochemically confirmed the upregulation of ET-1 in the epidermis of patients with AD or psoriasis. 28960333 2018
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.050 Biomarker disease BEFREE The aim of this study was to identify the putative link between two potential biomarkers (miR-31 and ET-1) in patients with psoriasis. 28937251 2017
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.050 Biomarker disease BEFREE Endothelin-1 and receptor A were detected in all patients with SCC and psoriasis, with a higher frequency and grade of expression than controls and BCC. 25946671 2015
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.050 Biomarker disease BEFREE As for the EDN1 -134 3A/4A gene polymorphism, no significant differences in genotype distributions were found between patients with either early- or late-onset psoriasis and control subjects (EDN1 -134 4A/4A: 9.6% in early-onset and 5.6% late-onset psoriasis vs 7.7% in controls; P > 0.05). 18031458 2007
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.050 GeneticVariation disease BEFREE The results seem to reflect a different susceptibility of MMP-2 as well as of some associated MMP-2 and ET-1 genotypes to psoriasis. 12077518 2002