EDN1, endothelin 1, 1906

N. diseases: 679; N. variants: 23
Disease: Raynaud Phenomenon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0034735
Disease: Raynaud Phenomenon
Raynaud Phenomenon 		0.020 Biomarker disease BEFREE Endothelin-1, sE-selectin and hsCRP concentrations in patients from both RP groups were significantly higher; concentration of HDL fraction was significantly lower compared with the control group. 31027378 2019
CUI: C0034735
Disease: Raynaud Phenomenon
Raynaud Phenomenon 		0.020 Biomarker disease BEFREE The findings indicate that the overproduction of ET-1 is a novel abnormal function in SSc fibroblasts, and that ET-1 induced by fibroblasts may play a role in the fibrosis and Raynaud's phenomenon of SSc. 7944634 1994