EDN1, endothelin 1, 1906

N. diseases: 679; N. variants: 23
Disease: Conn Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1384514
Disease: Conn Syndrome
Conn Syndrome 		0.020 AlteredExpression disease BEFREE Through EV mRNA profiling, 15 up-regulated and 4 down-regulated genes in patients with PA compared with EH were identified; moreover, EDN1 was expressed only in patients with PA. Microarray platform was validated by quantative real-time polymerase chain reaction on 4 genes ( CASP1, EDN1, F2R, and HMOX1) involved in apoptosis, inflammation, and endothelial dysfunction. 31230554 2019
CUI: C1384514
Disease: Conn Syndrome
Conn Syndrome 		0.020 AlteredExpression disease BEFREE We determined ET-1 levels in blood samples obtained during adrenal venous sampling of patients affected by PA (n=17). 19073831 2009