EGFR, epidermal growth factor receptor, 1956

N. diseases: 1394; N. variants: 183
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.340 Biomarker disease BEFREE <b>Methods</b>: The mice model of VAN drives AKI to CKD was developed to investigate the role and molecular mechanism of epidermal growth factor receptor (EGFR). 31131063 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.340 AlteredExpression disease BEFREE We previously demonstrated that wild type and mutant EGFRs repress the expression of the ARF tumor suppressor to promote the survival of lung tumor cells. 29959911 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.340 Biomarker disease BEFREE A multivariate logistic model with preoperative and surgical factors (age, gender, eGFR, proteinuria, hypertension, diabetes and type of cardiac surgery) demonstrated moderate discrimination for AKI (ROC AUC 0.76). 28302078 2017
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.340 AlteredExpression disease BEFREE These findings identify the Arf tumor suppressor as a new transcriptional target of nuclear EGFR and highlight Vps34 as an important regulator of the nuclear EGFR/Arf survival pathway. 26686095 2016
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.340 Therapeutic disease CTD_human Importance of functional EGF receptors in recovery from acute nephrotoxic injury. 14638913 2003