EN1, engrailed homeobox 1, 2019

N. diseases: 11; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.310 GeneticVariation disease BEFREE Several of the seven single nucleotide polymorphisms genotyped in the EN1 gene were associated with schizophrenia symptoms (smallest P value=0.0061) and the effects of antipsychotics on symptoms (smallest P value=2.4x10). 18698228 2008
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.310 GeneticVariation disease LHGDN Several of the seven single nucleotide polymorphisms genotyped in the EN1 gene were associated with schizophrenia symptoms (smallest P value=0.0061) and the effects of antipsychotics on symptoms (smallest P value=2.4x10). 18698228 2008
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.310 Biomarker disease PSYGENET Several of the seven single nucleotide polymorphisms genotyped in the EN1 gene were associated with schizophrenia symptoms (smallest P value=0.0061) and the effects of antipsychotics on symptoms (smallest P value=2.4x10). 18698228 2008
CUI: C0027626
Disease: Neoplasm Invasiveness
Neoplasm Invasiveness
0.300 Biomarker phenotype CTD_human DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer. 26213588 2015
CUI: C0027765
Disease: nervous system disorder
nervous system disorder
0.300 Biomarker group CTD_human Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults. 21892157 2011
CUI: C0010606
Disease: Adenoid Cystic Carcinoma
Adenoid Cystic Carcinoma
0.300 Biomarker disease CTD_human Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma. 16762588 2006
CUI: C0036095
Disease: Salivary Gland Neoplasms
Salivary Gland Neoplasms
0.300 Biomarker group CTD_human Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma. 16762588 2006
Malignant neoplasm of salivary gland
0.300 Biomarker disease CTD_human Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma. 16762588 2006
CUI: C0038987
Disease: Sweat Gland Neoplasms
Sweat Gland Neoplasms
0.010 AlteredExpression group BEFREE Engrailed homeobox 1 was expressed specifically in normal eccrine glands and was expressed in most of the tumour cells of sweat gland neoplasms with eccrine gland differentiation. 29436004 2018
CUI: C1368683
Disease: Epithelioma
Epithelioma
0.010 AlteredExpression disease BEFREE Expression of En1 was examined immunohistochemically in 111 cases of cutaneous epithelial neoplasms. 29436004 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 PosttranslationalModification group BEFREE Clinicopathologic correlation analyses indicated that EN1 methylation status is correlated with histologic tumor grade, tumor location, and final patient outcome. 21800291 2012
CUI: C0175754
Disease: Agenesis of corpus callosum
Agenesis of corpus callosum
0.010 Biomarker disease BEFREE Immunohistochemical analysis of EN1 in biopsy specimens obtained for diagnostic purposes and/or surgically resected material may reveal that EN1 is a biologic predictor of poor prognosis in patients with salivary ACC. 21800291 2012
CUI: C0282160
Disease: Aplasia Cutis Congenita
Aplasia Cutis Congenita
0.010 Biomarker disease BEFREE Immunohistochemical analysis of EN1 in biopsy specimens obtained for diagnostic purposes and/or surgically resected material may reveal that EN1 is a biologic predictor of poor prognosis in patients with salivary ACC. 21800291 2012