EPHA1, EPH receptor A1, 2041

N. diseases: 119; N. variants: 7
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.020 Biomarker disease BEFREE Eph receptor tyrosine kinases and their ephrin ligands are considered to play important roles in melanoma progression and metastasis. 23358429 2013
CUI: C0025202
Disease: melanoma
melanoma 		0.020 Biomarker disease BEFREE While a role for PTKs in human melanoma is less firmly established, human melanomas or melanoma cells have been reported to contain more tyrosine phosphate than normal melanocytes, and some receptor PTKs (EPH-A2/ ECK and EPH-B3) are overexpressed in over 90% of melanoma cell lines. 11095400 2000