EPO, erythropoietin, 2056

N. diseases: 646; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency
0.330 Biomarker disease BEFREE In subjects with normal renal function there was a strong exponential relation between hemoglobin and erythropoietin, whereas in renal impairment (eGFR < 60 mL/min/1.73m²) this relation was linear (men) or absent (women) (P < 0.001 for interaction). 25915923 2015
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency
0.330 Therapeutic disease CTD_human Protective effect of recombinant human erythropoietin against cisplatin-induced oxidative stress and nephrotoxicity in rat kidney. 22013135 2011
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency
0.330 GeneticVariation disease BEFREE Relation between renal dysfunction requiring renal replacement therapy and promoter polymorphism of the erythropoietin gene in cardiac surgery. 21092038 2010
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency
0.330 Biomarker disease BEFREE Patients with chronic renal insufficiency (CRI) have reduced hemoglobin levels, mostly as a result of decreased kidney production of erythropoietin, but the relation between renal insufficiency and the magnitude of hemoglobin reduction has not been well defined. 16138214 2005