ERBB2, erb-b2 receptor tyrosine kinase 2, 2064

N. diseases: 995; N. variants: 85
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004114
Disease: Astrocytoma
Astrocytoma
0.130 Biomarker disease BEFREE The strongest c-erbB-2 immunoexpression was observed in low grade astrocytomas (diffuse astrocytomas G2); in the glioblastoma group the c-erbB-2 protein expression was weak and 17.4% of cases were negative. 21804458 2011
CUI: C0004114
Disease: Astrocytoma
Astrocytoma
0.130 AlteredExpression disease BEFREE c-erbB-2 in astrocytomas: infrequent overexpression by immunohistochemistry and absence of gene amplification by fluorescence in situ hybridization. 8605096 1996
CUI: C0004114
Disease: Astrocytoma
Astrocytoma
0.130 AlteredExpression disease BEFREE Neu receptor protein showed increased expression in malignant astrocytomas (including glioblastomas) and severe reactive gliosis. 8826951 1996
CUI: C0004114
Disease: Astrocytoma
Astrocytoma
0.130 Biomarker disease HPO