Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
0.360 Biomarker disease BEFREE The current meta-analyses results suggest that the XPD gene, but not the EGF gene, has contributed to CM susceptibility, and XPD is a possible drug target. 25537294 2015
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
0.360 GeneticVariation disease BEFREE On stratified analysis by tumor type, XPD Lys751Gln polymorphism was not associated with increased risk of non-melanoma skin cancer, but was significantly related with increased risk of cutaneous melanoma (Gln/Gln vs Lys/Lys: OR=1.15, 95%CI=1.02-1.29, p=0.023; dominant model: OR=1.09, 95%CI=1.01-1.18, p=0.036). 25169498 2014
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
0.360 GeneticVariation disease BEFREE Therefore, the meta-analysis suggests that there is a significant association between ERCC2 Lys751Gln polymorphism and susceptibility to cutaneous melanoma. 23494240 2013
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
0.360 GeneticVariation disease BEFREE Thus, ERCC5 codon 1104 and ERCC2 codon 751 polymorphisms are independent prognostic factors in patients with cutaneous melanoma. 21390047 2011
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
0.360 Biomarker disease BEFREE We concluded that genetic variants of the XPD gene might serve as biomarkers for susceptibility to cutaneous melanoma. 17164380 2006
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
0.360 GeneticVariation disease BEFREE XPD gene polymorphism and host characteristics in the association with cutaneous malignant melanoma risk. 14735199 2004
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
0.360 CausalMutation disease CGI