Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine
0.030 GeneticVariation disease BEFREE Overall, no relevant common findings emerge among the studies, except for some statistically significant associations between polymorphisms in the XRCC1 and XPD genes, mainly for colorectal adenoma risk. 17419091 2007
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine
0.030 GeneticVariation disease BEFREE We used a case-control study design (157 carcinomas, 983 adenomas and 399 controls) to test the association between five polymorphisms in these DNA repair genes (XRCC1 Arg194Trp, Arg280His, Arg399Gln, XRCC3 Thr241Met and XPD Lys751Gln), and risk of colorectal adenomas and carcinomas in a Norwegian cohort. 16542436 2006
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine
0.030 GeneticVariation disease BEFREE XRCC1, XRCC3, and XPD polymorphisms as modifiers of the effect of smoking and alcohol on colorectal adenoma risk. 17164360 2006