Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.020 AlteredExpression disease BEFREE Obesity or a high-fat diet represses the endoribonuclease activity of inositol-requiring enzyme 1α (IRE1α), a transducer of the unfolded protein response (UPR) in cells under endoplasmic reticulum (ER) stress. 29764990 2018
CUI: C0028754
Disease: Obesity
Obesity
0.020 Biomarker disease BEFREE The macrophage IRE1α pathway drives obesity and metabolic syndrome through impairing BAT activity and WAT browning. 28346409 2017