Disease: Tumor Progression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.030 Biomarker phenotype BEFREE This study provides the first demonstration of a dual role of IRE1 downstream signaling in cancer and opens a new therapeutic window to abrogate tumor progression. 29311133 2018
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.030 Biomarker phenotype BEFREE In this model, two key mechanisms of tumor progression and cancer cell survival are functionally linked to IRE1α. 26325176 2015
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.030 AlteredExpression phenotype BEFREE The activation of the UPR sensor IRE1α has been described to play an important role in tumor progression. 22718352 2012