ESR1, estrogen receptor 1, 2099

N. diseases: 1101; N. variants: 185
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 Biomarker group BEFREE Adding dichotomous tumor ER or PR status to the panel of standard predictors did not improve both model discrimination and calibration.<b>Conclusions:</b> Obesity may be associated with greater endometrial tumor expression of ER and PR. 28052940 2017
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 Biomarker group CTD_human Activating ESR1 mutations in hormone-resistant metastatic breast cancer. 24185510 2013
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 AlteredExpression group LHGDN Oestrogen receptor gene (ESR1) amplification is frequent in endometrial carcinoma and its precursor lesions. 18720455 2008
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 Biomarker group LHGDN Immunohistochemical analysis of c-myc, c-jun and estrogen receptor in normal, hyperplastic and neoplastic endometrium. 15800680 2005
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 Biomarker group LHGDN Impact of the nuclear receptor coactivator AIB1 isoform AIB1-Delta3 on estrogenic ligands with different intrinsic activity. 14691461 2004
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 AlteredExpression group LHGDN Overexpression of estrogen receptor-alpha gene suppresses gap junctional intercellular communication in endometrial carcinoma cells. 14762440 2004
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 AlteredExpression group LHGDN Overexpression of estrogen receptor-alpha in the endometrial carcinoma cell line Ishikawa: inhibition of growth and angiogenic factors. 15581976 2004
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 AlteredExpression group LHGDN CYP1B1 gene polymorphisms have higher risk for endometrial cancer, and positive correlations with estrogen receptor alpha and estrogen receptor beta expressions. 12873984 2003
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 GeneticVariation group LHGDN Association of estrogen receptor alpha and beta3-adrenergic receptor polymorphisms with endometrial cancer. 12962933 2003
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 PosttranslationalModification group LHGDN Coordinate expression of Cdc25B and ER-alpha is frequent in low-grade endometrioid endometrial carcinoma but uncommon in high-grade endometrioid and nonendometrioid carcinomas. 14559803 2003
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 AlteredExpression group LHGDN Estrogen receptor-mediated effects of tamoxifen on human endometrial cancer cells. 12088871 2002
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.400 GeneticVariation group BEFREE Relative proportions of the estrogen receptor (ER) alternatively spliced mRNA variants from the proximal (A) and distal (B) promoter pre-mRNA transcripts were measured in normal human uterus, an endometrial tumor, and in T47D, MCF-7, and BT-20 breast tumor cell lines. 9685214 1998