|
Myocardial Infarction
|
0.400 |
Biomarker
|
disease |
BEFREE |
Thrombolytic Therapy in the Current ERA: Myocardial Infarction and Beyond.
|
29283052 |
2018 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The aim of the study was to investigate the role of estrogen receptor type 2 gene (ESR2) variant G1730A in myocardial infarction (MI) in young age.
|
30036658 |
2018 |
|
Myocardial Infarction
|
0.400 |
Biomarker
|
disease |
BEFREE |
By merging these FFLs, the first miRNA and TF mediated regulatory network for MI was constructed, from which four regulators (SP1, ESR1, miR-21-5p and miR-155-5p) and three regulatory modules that might play crucial roles in MI were then identified.
|
26258537 |
2015 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
An association of the common ESR1 -397T>C and -351A>G polymorphisms and of other polymorphisms with cardiovascular disease and with myocardial infarction is still not firmly established.
|
22061094 |
2012 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The -351A/G polymorphism of ESR1 is associated with risk of myocardial infarction but not with extreme longevity.
|
20599431 |
2010 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
No significant association between ESR1 rs2234693 and MI was observed in our sample or in the meta-analysis (16 studies; N approximately 32,000; OR approximately 1).
|
19608186 |
2009 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Recently, single nucleotide polymorphisms (SNPs) of the estrogen receptor alpha (ESR-1) gene (c.454-397T>C) associated with the prognosis of myocardial infarction in postmenopausal women were identified; however, the mechanism by which genetic variation of ESR-1 contributes to the pathogenesis of CVD is unknown.
|
19556726 |
2009 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The estrogen receptor-1 (ESR1, c.454-397T>C) CC variant genotype is associated with the severity of coronary artery disease (CAD) and an increased risk of myocardial infarction in men.
|
17558892 |
2007 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Estrogen receptor alpha gene variation is associated with risk of myocardial infarction in more than seven thousand men from five cohorts.
|
16484614 |
2006 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The reported association has the potential to explain the risks associated with estrogen use in certain women and a recent report of association between an ESR1 haplotype comprised of c.454-397 T and c.454-351 A alleles with increased myocardial infarction and ischaemic heart disease, independent of the standard, established cardiovascular risk factors.
|
16014638 |
2005 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In previous association studies, the -397T/C (rs2234693) and -351A/G (rs9340799) single nucleotide polymorphisms in the estrogen receptor alpha gene (ESR1) have been implicated in the risk of coronary atherosclerosis and myocardial infarction.
|
16203927 |
2005 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
To determine whether the ESR1 haplotype created by the c.454-397T>C (PvuII) and c.454-351A>G (XbaI) polymorphisms is associated with myocardial infarction (MI) and IHD risk.
|
15213208 |
2004 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
Whether ESR1 c.454-397T>C is causally related to MI risk or in linkage disequilibrium with 1 or more causal variants remains to be determined.
|
14600184 |
2003 |
|
Myocardial Infarction
|
0.400 |
Biomarker
|
disease |
CTD_human |
Whether ESR1 c.454-397T>C is causally related to MI risk or in linkage disequilibrium with 1 or more causal variants remains to be determined.
|
14600184 |
2003 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We may conclude that in Caucasian women the length of the dinucleotide (TA) repeat in the regulatory region of the alpha-estrogen receptor gene is neither associated with premature myocardial infarction nor with serum lipid levels.
|
12824724 |
2003 |
|
Myocardial Infarction
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Whether ESR1 c.454-397T>C is causally related to MI risk or in linkage disequilibrium with 1 or more causal variants remains to be determined.
|
14600184 |
2003 |