Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
There are significant differences in allelic distributions for rs2234693 and rs9340799 in ESR1 gene between patients with migraine and control subjects.
|
27778160 |
2017 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Both 325C>G and 594G>A polymorphisms showed no major effects either in males or in females.Based on the statistical data, we conclude some of the ESR1 gene polymorphisms may have major contributions to the pathogenesis of migraine in Caucasian populations.
|
26334887 |
2015 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Univariate analysis revealed significant associations of polymorphisms in CYP19A1, ESR1, TNFA and PRDM16 genes with migraine susceptibility.
|
24698360 |
2014 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Three haplotypes in ESR1 were found to be associated with migraine ( P = 0.004, 0.03, 0.005).
|
23674830 |
2013 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Potential role of aromatase over estrogen receptor gene polymorphisms in migraine susceptibility: a case control study from North India.
|
22511967 |
2012 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Effect estimates from an additive model suggest that the ESR-1 594 G>A (pooled OR 1.37; 95% CI 1.02-1.83) and ESR-1 325 C>G (pooled OR 1.16; 95% CI 1.03-1.32) variants are associated with any migraine.
|
20959426 |
2010 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
We found significant association of TT genotype [odds ratio (OR) 3.458, confidence interval (CI) 1.757, 6.806; P = 0.0003] and T allele (OR 1.729, CI 1.309, 2.284; P = 0.0001) of ESR1 PvuII single nucleotide polymorphism with migraine when compared with HC.
|
19673915 |
2010 |
Migraine Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
Our study does not support a major contribution of ESR1 and PGR to the pathogenesis of migraine.
|
19175383 |
2009 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Using the SUMSTAT program, we observed ESR2-ESR1-FSHR significant gene-gene interaction, suggesting association with the MA/MO phenotype (P = .005; P = .003 in females), and with MA alone (P = .021; P = .030 for females).We corroborated that ESR2-ESR1-FSHR haplotypes interacted for migraine under a model-free hypothesis (empirical P = .010 for the whole sample; P = .001 for females), and the association was stronger for the MA phenotype alone (empirical P = 5.0e-4, under the heterogeneity model; P = .001 for females).
|
19093296 |
2009 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
In this study, we tested the association of two female hormonal genes, progesterone receptor (PGR) and estrogen receptor (ESR1), which were previously reported to be associated with migraine in women.
|
17609999 |
2007 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
No role for estrogen receptor 1 gene intron 1 Pvu II and exon 4 C325G polymorphisms in migraine susceptibility.
|
16504171 |
2006 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Therefore, we conclude that ESR1 G325C polymorphism is associated with migraine in our population.
|
16361951 |
2006 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Therefore, we conclude that ESR1 G325C polymorphism is associated with migraine in our population.
|
16361951 |
2006 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
There were no differences in the genotype distributions of the previously migraine-associated SNPs C677T (MTHFR) and G2014A (ESR1) between cases and controls (P-values 0.83 and 0.55, respectively).
|
17116097 |
2006 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Interaction analysis of the PROGINS variant with our previously reported associated ESR1 594A variant showed that individuals who possessed at least one copy of both risk alleles were 3.2 times more likely to suffer migraine.
|
15654614 |
2005 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
In another publication, other ESR1 variation was associated with migraine.
|
16179580 |
2005 |
Migraine Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
This study thus examined the estrogen receptor 1 (ESRalpha) gene for a potential role in migraine pathogenesis and susceptibility.
|
15133719 |
2004 |
Migraine Disorders
|
0.400 |
GeneticVariation
|
group |
LHGDN |
A population-based cohort of 224 migraine sufferers and 224 matched controls were genotyped for the G594A polymorphism located in exon 8 of the ESR1 gene.
|
15133719 |
2004 |
Migraine Disorders
|
0.400 |
Biomarker
|
group |
CTD_human |
A population-based cohort of 224 migraine sufferers and 224 matched controls were genotyped for the G594A polymorphism located in exon 8 of the ESR1 gene.
|
15133719 |
2004 |