ESR2, estrogen receptor 2, 2100

N. diseases: 528; N. variants: 56
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.340 Biomarker group BEFREE Our preliminary study on repressing colorectal tumors by recombinant adenoviruses (Ads) delivering the human ERβ gene (Ad-ERβ) has achieved positive result. 24531912 2014
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.340 AlteredExpression group BEFREE Expression of ERbeta resulted in inhibition of proliferation and G(1) phase cell cycle arrest and this effect was dependent on a functional DNA-binding region. c-Myc is overexpressed in an overwhelming majority of colorectal tumors. 19602591 2009
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.340 GeneticVariation group LHGDN Sex-specific differences in the expression levels of estrogen receptor subtypes in colorectal cancer. 18727987 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.340 Biomarker group CTD_human ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates. 15954165 2005
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.340 Biomarker group LHGDN Expression of estrogen receptor beta in human colorectal cancer. 14716825 2004