ESR2, estrogen receptor 2, 2100

N. diseases: 528; N. variants: 56
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation disease GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901 2019
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation disease GWASCAT Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. 29700475 2018
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 Biomarker disease BEFREE No association of ESR2 G×E interaction with MDD was found in the reproductive group. 27814959 2017
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation disease BEFREE Estrogen receptor alpha (ESR1) and beta (ESR2) are known to regulate gene expression and estrogen response in areas of the brain associated with major depression and are unlikely to be correlated with exogenous factors that may influence depression. 26169989 2015
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation disease BEFREE The results suggest that shorter length of AR and ER beta gene microsatellites might influence the onset of MDD in female adolescents, a further elucidation of the mechanisms is warranted. 17365134 2007
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 Biomarker disease PSYGENET The results suggest that shorter length of AR and ER beta gene microsatellites might influence the onset of MDD in female adolescents, a further elucidation of the mechanisms is warranted. 17365134 2007