MECOM, MDS1 and EVI1 complex locus, 2122

N. diseases: 191; N. variants: 57
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.330 Biomarker disease CTD_human SUMO1 negatively regulates the transcriptional activity of EVI1 and significantly increases its co-localization with EVI1 after treatment with arsenic trioxide. 23770046 2013
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.330 AlteredExpression disease BEFREE Overexpression of EVI1 in ovarian cancer has led to a proposed oncogenic role. 20462630 2010
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.330 Biomarker disease BEFREE Amplification of MDS1/EVI1 and EVI1, located in the 3q26.2 amplicon, is associated with favorable patient prognosis in ovarian cancer. 17409414 2007
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.330 Biomarker disease BEFREE Immunostaining of ovarian cancer cell lines revealed nuclear EVI-1 protein. 8932329 1996