ALB, albumin, 213

N. diseases: 1198; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE One study met our inclusion criteria (26 children with minimal change nephrotic syndrome) and 11 were excluded (nine cross-over studies, one where albumin was not used for nephrotic syndrome and one where authors did not state whether the children had oedema). 31425606 2019
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE The SFCT in patients with NS was correlated with age (r = - 0.307, p = 0.003), body height (r = - 0.320, p = 0.022), body weight (r = - 0.343, p = 0.014), axial length (AL, r = - 0.237, p = 0.023), total protein (TP, r = - 0.302, p = 0.031), albumin (ALB, r = - 0.285, p = 0.042), prealbumin (PA, r = - 0.303, p = 0.033) and 24-h urine volume (UV, r = - 0.298, p = 0.034). 30727992 2019
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE Comparing NS and non-NS groups, significance differences were shown in hypertension (HTN), 24-h urine protein, serum albumin, serum creatine, eGFR and uric acid. 31542837 2019
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 AlteredExpression group BEFREE Glycated albumin level is significantly decreased in patients suffering nephrotic syndrome. 30905459 2019
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE Furthermore, incubation with plasma from patients with post-transplant recurrence of nephrotic syndrome increased albumin permeability in rat glomeruli compared to remission plasma. 29433915 2018
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE Children with NS who were hypertensive, had higher urinary protein excretion and low serum albumin were more prone to develop AKI. 30288260 2018
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE Glomerular filtration rate (GFR) remained normal and she never developed frank nephrotic syndrome (average albumin 31 g/L). 30141175 2018
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE What is New: • Urinary potassium to the sum of urinary potassium plus sodium ratio can accurately detect hypovolemia in nephrotic syndrome and thus identify those children who would probably respond to albumin infusion. 29022080 2018
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE Lemmings into the sea or back across the bridge? The fate of albumin in nephrotic syndrome. 29389392 2018
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE Abolishment of proximal tubule albumin endocytosis does not affect plasma albumin during nephrotic syndrome in mice. 29032953 2018
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 AlteredExpression group BEFREE Her initial serum albumin level was 12 g/L, and a 24-hour urine protein output was quantified at 8.14 g/day; she was diagnosed as having nephrotic syndrome. 29740522 2018
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE The primary outcome measure was time to remission of nephrotic syndrome (defined as normalization of serum albumin). 28852480 2017
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE In these patients, restoring the liquid homeostasis is a challenge, but some key points can help the physicians with first-line management: 1) carefully evaluate the signs of hypovolemia (edematous state can be misleading); 2) bear in mind that-in hypovolemic, severely hypoalbuminemic (serum albumin levels < 2 g/dL) NS children-initial fluid administration should be followed by a 20% albumin infusion if oligoanuria persists; intravenous 4.5% albumin may be a valid alternative as a first-line therapy instead of crystalloid and 20% albumin; and 3) pay attention when using furosemide; it should only be administered after albumin infusion or after hypovolemia correction. 28209267 2017
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE Urine samples from 5 patients with nephrotic syndrome were subjected to acetone precipitation and albumin/immunoglobulin G depletion prior to analysis by two‑dimensional liquid chromatography tandem mass spectrometry. 28849145 2017
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 AlteredExpression group BEFREE The occurrence of relapse or persistence of proteinuria had negative effects on renal survival in iMN patients with NS, and low serum albumin levels at baseline were associated with non-achievement of sCR and progression to NS. 28347297 2017
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE The aim here was to analyze albumin use among patients with nephrotic syndrome. 28443947 2017
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE Lower serum albumin is a strong independent predictor for VTE events in NS. 28391310 2017
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 GeneticVariation group BEFREE Low albumin:globulin (A/G) ratios are associated with vascular adverse events, nephrotic syndrome and autoimmune disease. 23303382 2013
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group CTD_human Nephrotic syndrome (NS) is characterized by marked urinary excretion of albumin and other intermediated-size plasma proteins such as transferrin. 17178036 2006
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 AlteredExpression group BEFREE No correlation between the outcome of the patients with nephrotic syndrome and the degree of proteinuria and/or serum albumin levels at the initiation of treatment were noted. 11760404 2002
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE In both the nephrotic syndrome (NS) and hereditary analbuminemia in the Nagase analbuminemic rat (NAR), the plasma protein concentration is nearly normal since albumin is replaced by several high molecular weight proteins. 9453001 1998
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group CTD_human Experimental proliferative glomerulonephritis in the cat. 1556257 1992
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
0.400 Biomarker group BEFREE This observation is consistent with a hypothesis that increased renal catabolism contributes to total albumin catabolism in nephrosis. 2256474 1990