ALB, albumin, 213

N. diseases: 1198; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE Univariate analysis revealed shorter ECMO duration, higher body mass index, preimplantation creatinine > 100 mmol/l, lower preimplantation serum albumin, and the development of stroke or limb ischemia on ECMO to be significantly associated with mortality while on ECMO. 30864968 2020
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy. 30458203 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 GeneticVariation group BEFREE CVD incidence (CVD death, myocardial infarction (MI), stroke, revascularization, angina, or ischemic electrocardiogram) was associated with diabetes duration, most recent albumin excretion rate (AER), updated mean triglycerides, baseline hypertension, baseline LDL cholesterol, and most recent HbA<sub>1c</sub> Major atherosclerotic cardiovascular events (CVD death, MI, or stroke) were associated with diabetes duration, most recent AER, baseline systolic blood pressure, baseline smoking, and updated mean HbA<sub>1c</sub> Compared with findings in DCCT/EDIC, traditional risk factors similarly predicted CVD; however AER predominates in EDC and HbA<sub>1c</sub> in DCCT/EDIC. 30409781 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE Adjustments were made for: age; gender; history of stroke and hypertension; systolic blood pressure; lipid-lowering, antiplatelet and antihypertensive medications; laboratory profiles including hemoglobin, serum albumin, calcium, triglyceride, total and low-density lipoprotein cholesterol; and apolipoprotein A1. 31498021 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE We identified 4 risk factors for acute heart failure after stroke: atrial fibrillation (odds ratio [OR], 5.9; 95% confidence interval [CI], 2.5-14.0; P < .001), history of cardiac disease (OR, 3.6; 95% CI, 1.3-9.1; P = .01), Glasgow Coma Scale score ≤ 8 (OR, 4.5; 95% CI, 1.7-12.0; P = .003), and serum albumin < 35 g/L (OR, 3.4; 95% CI, 1.4-8.4; P = .008). 30930241 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE Cox proportional hazard analysis revealed that high IS/low albumin (hazard ratio (HR): 5.33; 95% confidence interval (CI): 1.71-16.5; P < 0.01), diastolic pressure (HR: 0.94; 95% CI: 0.91-0.98; P < 0.01), prior stroke (HR: 4.54; 95% CI: 1.33-15.4; P = 0.01), and left ventricular ejection fraction (LVEF) (HR: 0.92; 95% CI: 0.88-0.96; P < 0.001) were associated with increased mortality. 30464134 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE Excess urinary albumin excretion is more strongly associated with incident stroke and coronary heart disease risk in black than in white individuals. 31047019 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 AlteredExpression group BEFREE The positive association of hypertension and albumin levels with cognitive functioning and the negative association of stroke occurrence with cognitive functioning were replicated in both countries. 30786950 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE Strong correlates predicting survival were estimated glomerular filtration rate (eGFR), serum albumin, extracorporeal membrane oxygenation, ventricular assist device, mechanical ventilation, peak oxygen capacity, hemodynamics, inotrope support, and type of heart disease with less predictive variables including antiarrhythmic agents, history of stroke, vascular disease, prior malignancy, and prior tobacco use. 30659754 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 AlteredExpression group BEFREE Multiple regression analysis with the total Japanese version of the Montreal Cognitive Assessment score as the dependent variable showed that the serum albumin level, serum globulin level, serum A/G ratio, C-reactive protein, years of formal education and sex were related to the Japanese version of the Montreal Cognitive Assessment total score at the age of 70 years, and that the serum albumin level, serum globulin level, serum A/G ratio, C-reactive protein, years of formal education and stroke were related at the age of 80 years. 31461209 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE Linear regression predicted factors for 34% of the variance in albumin were activities of daily living (ADL), gender, stroke and cancer. 28988219 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 AlteredExpression group BEFREE Relatively low serum albumin levels are associated with the development of several geriatric diseases, including stroke and poor cognitive performance. 30249938 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE The ability of cardiovascular biomarkers to predict the incidence of stroke subtypes remains ill-defined in the general population.Methods and Results:The blood levels of B-type natriuretic peptide (BNP) and high-sensitivity C-reactive protein (hs-CRP) and urinary albumin corrected by urinary creatinine (UACR) were determined in a general population (n=13,575). 29386475 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 AlteredExpression group BEFREE Patients' characteristics (including age, gender, past history), National Institute of Health Stroke Scale and serum albumin level on admission, concomitant medications associated with SAP prevention (including cilostazol), and stroke characteristics (bilateral subcortical white matter lesion, brainstem involvement, large infarction, and asymptomatic hemorrhagic infarction) were compared between the SAP(-) and SAP(+) groups. 29680945 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 GeneticVariation group BEFREE The masked hypertension group had a greater risk for stroke compared with the controlled BP group (hazard ratio, 2.77; 95% CI, 1.20-6.37), independent of traditional cardiovascular risk factors, urine albumin to creatinine ratio, and circulating B-type natriuretic peptide levels. 29800067 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 GeneticVariation group BEFREE Lower concentrations of serum albumin appear to be associated with an increased risk of all-cause and cardiovascular mortality, coronary heart disease, heart failure and stroke. 29573083 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE Stroke onset was associated with the development and subsequent expansion of cerebrum volume, herniation, hematoma and plasma albumin extravasation. 30114508 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 GeneticVariation group BEFREE Cox proportional hazards analyses revealed that lower body mass index (hazard ratio [HR] = 0.89, 95% confidence interval [CI] = 0.82-0.98, P = 0.03) and prior stroke (HR = 2.34, 95%CI = 1.10-4.85, P = 0.03) were independent predictors of all-cause death, and lower serum albumin (HR = 0.44, 95%CI = 0.22-0.92, P = 0.03) along with currently smoking (HR = 4.73, 95%CI = 1.43-14.1, P = 0.01) were independent predictors of major amputation in HD patients. 28593656 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group BEFREE Using the albumin in acute stroke (ALIAS) trials dataset, patients with anterior circulation stroke were included for analysis. 27593522 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Therapeutic group CTD_human Oxidative and nitrosative stress in acute ischaemic stroke. 17270091 2007
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group CTD_human Oxidative and nitrosative stress in acute ischaemic stroke. 17270091 2007
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Therapeutic group CTD_human After adjusting for the tPA effect, the probability of good outcome (defined as modified Rankin Scale 0 to 1 or NIH Stroke Scale 0 to 1 at 3 months) at the highest three ALB doses was 81% greater than in the lower dose-tiers (relative risk [RR], 1.81; 95% confidence interval [CI], 1.11 to 2.94) and was 95% greater than in the comparable NINDS rt-PA Stroke Study cohort (RR, 1.95; 95% CI, 1.47 to 2.57). 16809570 2006
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group CTD_human After adjusting for the tPA effect, the probability of good outcome (defined as modified Rankin Scale 0 to 1 or NIH Stroke Scale 0 to 1 at 3 months) at the highest three ALB doses was 81% greater than in the lower dose-tiers (relative risk [RR], 1.81; 95% confidence interval [CI], 1.11 to 2.94) and was 95% greater than in the comparable NINDS rt-PA Stroke Study cohort (RR, 1.95; 95% CI, 1.47 to 2.57). 16809570 2006
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Therapeutic group CTD_human High dose human serum albumin for the treatment of acute ischemic stroke: a safety study. 16174931 2004
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.400 Biomarker group CTD_human High dose human serum albumin for the treatment of acute ischemic stroke: a safety study. 16174931 2004