Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 Biomarker disease BEFREE Gene expression was examined to reveal the molecular mechanism underlying the roles of EZH2 in endometrial cancer. 31640461 2020
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 AlteredExpression disease BEFREE We investigated patterns of EZH2 expression in endometrial cancer. 31843273 2020
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 Biomarker disease BEFREE Additionally, small interfering RNA was used to investigate the role of EZH2 in endometrial carcinoma cell proliferation, and the results showed that EZH2 knockdown suppressed the proliferation of endometrial carcinoma cells <i>in vitro</i>. 29805666 2018
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 Biomarker disease BEFREE This study aimed to investigate the effect of miR-101-3p on autophagy in endometrial carcinoma (EC) cells and the connection between miR-101-3p and EZH2. 29691644 2018
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 AlteredExpression disease BEFREE Endometrial carcinoma RL-952 cells were transfected with chemically synthesized siRNA to conduct targeting inhibition of EZH2 expression. 29344151 2017
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 Biomarker disease BEFREE Our findings suggest that EZH2 drives EC progression by regulating miR-361/Twist signaling, and support EZH2 inhibition as a promising anti-EC therapeutic strategy. 28088786 2017
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 Biomarker disease BEFREE Further studies should explore the therapeutic potential of inhibiting EZH2 in patients with endometrial cancer. 28418882 2017
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 Biomarker disease BEFREE The microRNA-101-EZH2/MCL-1/FOS axis is a potential therapeutic target for endometrial cancer. 25153722 2014
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 AlteredExpression disease BEFREE Enhancer of zeste homolog 2 protein expression was increased in all 3 cancer cell lines and human endometrial cancer tissue specimens relative to control. 23792601 2013
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.390 Biomarker disease CTD_human Down-regulation of the histone methyltransferase EZH2 contributes to the epigenetic programming of decidualizing human endometrial stromal cells. 21903722 2011