Colon Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We found that there was a positive association between EZH2 and H2B<sup>Y37ph</sup> in colon cancer tissues and cells.
|
31283006 |
2020 |
Colon Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
For this reason, we immunohistochemically analyzed EZH2 expression in 105 specimens from colon cancer patients separately for tumor center and invasion front.
|
31317325 |
2019 |
Colon Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Inhibition of NF-κB substantially reduced EZH2 transcription and restored their mRNAs as well as the production of normal Siglec ligand glycans in the results obtained from in vitro studies on cultured colon cancer cell lines.
|
30716533 |
2019 |
Colon Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Long noncoding RNA PCAT6 inhibits colon cancer cell apoptosis by regulating anti-apoptotic protein ARC expression via EZH2.
|
30569799 |
2019 |
Colon Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We demonstrated that AcK27-HOXB9 inhibits while non-acetylated HOXB9 promotes EZH2 expression and colon cancer progression.
|
29654889 |
2018 |
Colon Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we reported that EZH2 is significantly enriched in the promoter region of WNT5A after TGF-β induction in SW480 colon cancer cell line, which in turn silenced the expression of WNT5A.
|
28748258 |
2017 |
Colon Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
EZH2 is functionally considered to suppress miR-31 expression in human cancers; however, no study has reported its relationship with colon cancer.
|
26871294 |
2016 |
Colon Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.
|
27634879 |
2016 |
Colon Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Here, we demonstrated that miR-506 was down-regulated in colon cancer tissue and cells and that miR-506 expression was inversely correlated with EZH2 expression, tumor size, lymph node invasion, TNM stage and metastasis.
|
26452129 |
2015 |
Colon Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Since co-inhibition of both EGFR and EZH2 has not been studied in colon cancer, we examined the effects of co-inhibition of EGFR and EZH2 on 2 colon cancer cell lines, HT-29 and HCT-15.
|
25535899 |
2014 |
Colon Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
EZH2 regulates cofilin activity and colon cancer cell migration by targeting ITGA2 gene.
|
25549357 |
2014 |
Colon Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Abrogation of EZH2 expression impairs the ability of colon cancer cells to move associated with anoikis in three-dimensional environment.
|
23116973 |
2013 |
Colon Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Whole genome transcriptome analyses identified cellular genes affected by EZH2 depletion in colon cancer cell lines.
|
21765901 |
2011 |