FGFR1, fibroblast growth factor receptor 1, 2260

N. diseases: 816; N. variants: 119
Disease: Urothelial Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.030 Biomarker disease BEFREE BGJ398, A Pan-FGFR Inhibitor, Overcomes Paclitaxel Resistance in Urothelial Carcinoma with FGFR1 Overexpression. 30326563 2018
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.030 Biomarker disease BEFREE These results indicate that inhibition of FGFR1 and wild-type or mutant FGFR3 may represent a useful therapeutic approach in patients with both non-muscle invasive and muscle invasive UC. 21119661 2011
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.030 Biomarker disease BEFREE Our results indicate that FGFR1 has significant effects on urothelial cell phenotype and may represent a useful therapeutic target in some cases of urothelial carcinoma. 19458078 2009