Spondylometaphyseal dysplasia, 'corner fracture' type
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
"Novel fibronectin mutations and expansion of the phenotype in spondylometaphyseal dysplasia with ""corner fractures""."
|
30599297 |
2019 |
Spondylometaphyseal dysplasia, 'corner fracture' type
|
0.700 |
GeneticVariation
|
disease |
UNIPROT |
"Mutations in Fibronectin Cause a Subtype of Spondylometaphyseal Dysplasia with ""Corner Fractures""."
|
29100092 |
2017 |
Spondylometaphyseal dysplasia, 'corner fracture' type
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
"Mutations in Fibronectin Cause a Subtype of Spondylometaphyseal Dysplasia with ""Corner Fractures""."
|
29100092 |
2017 |
Spondylometaphyseal dysplasia, 'corner fracture' type
|
0.700 |
GermlineCausalMutation
|
disease |
ORPHANET |
"Mutations in Fibronectin Cause a Subtype of Spondylometaphyseal Dysplasia with ""Corner Fractures""."
|
29100092 |
2017 |
Spondylometaphyseal dysplasia, 'corner fracture' type
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
"Mutations in Fibronectin Cause a Subtype of Spondylometaphyseal Dysplasia with ""Corner Fractures""."
|
29100092 |
2017 |
GLOMERULOPATHY WITH FIBRONECTIN DEPOSITS 2 (disorder)
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Mutations in FN1 cause glomerulopathy with fibronectin deposits.
|
18268355 |
2008 |
GLOMERULOPATHY WITH FIBRONECTIN DEPOSITS 2 (disorder)
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Mutations in FN1 cause glomerulopathy with fibronectin deposits.
|
18268355 |
2008 |
GLOMERULOPATHY WITH FIBRONECTIN DEPOSITS 2 (disorder)
|
0.700 |
GermlineCausalMutation
|
disease |
ORPHANET |
Mutations in FN1 cause glomerulopathy with fibronectin deposits.
|
18268355 |
2008 |
GLOMERULOPATHY WITH FIBRONECTIN DEPOSITS 2 (disorder)
|
0.700 |
GeneticVariation
|
disease |
UNIPROT |
Mutations in FN1 cause glomerulopathy with fibronectin deposits.
|
18268355 |
2008 |
Spondylometaphyseal dysplasia, 'corner fracture' type
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
GLOMERULOPATHY WITH FIBRONECTIN DEPOSITS 2 (disorder)
|
0.700 |
Biomarker
|
disease |
CTD_human |
|
|
|
GLOMERULOPATHY WITH FIBRONECTIN DEPOSITS 2 (disorder)
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
Malignant neoplasm of breast
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Extra domain A-containing fibronectin expression in Spin90-deficient fibroblasts mediates cancer-stroma interaction and promotes breast cancer progression.
|
31637720 |
2020 |
Malignant neoplasm of breast
|
0.600 |
Biomarker
|
disease |
BEFREE |
The extracellular matrix protein fibronectin (FN) facilitates tumorigenesis and the development of breast cancer.
|
31000696 |
2019 |
Malignant neoplasm of breast
|
0.600 |
Biomarker
|
disease |
BEFREE |
We recently showed that fibronectin (FN) leads to Tam resistance and selection of breast cancer stem cells.
|
31812165 |
2019 |
Diabetic Nephropathy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In addition, intravenous administration of KLPPR resulted in excellent kidney-targeted distribution and low urinary excretion in mice with streptozocin-induced diabetic nephropathy (DN), lowered the parameters of urea nitrogen, serum creatinine and kidney index, as well as facilitated the recovery of renal physiological function in improving the levels of urinary creatinine and the creatinine clearance rate by suppressing secretion and accumulation of fibronectin and TGF-β1.
|
31534545 |
2019 |
Malignant neoplasm of breast
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Fibronectin levels were higher (P = 0.014) in patients infected with HCV than noninfected BC patients.
|
29285674 |
2018 |
Malignant neoplasm of breast
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Using publicly available clinical data, we observed that high FN expression was associated with poor prognosis in patients with breast cancer.
|
29628980 |
2018 |
Malignant neoplasm of breast
|
0.600 |
Biomarker
|
disease |
BEFREE |
Enhanced antitumor and anti-metastasis efficacy against aggressive breast cancer with a fibronectin-targeting liposomal doxorubicin.
|
29277681 |
2018 |
Malignant neoplasm of breast
|
0.600 |
Biomarker
|
disease |
BEFREE |
Autocrine Fibronectin Inhibits Breast Cancer Metastasis.
|
29934326 |
2018 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
MiR-192 causes degradation of TGF-β1 and FN through targeting Egr1 and affects the progression of TIF and even DN.
|
30024615 |
2018 |
Diabetic Nephropathy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Increased ColIV and FN levels may be partially responsible for the development of DN.
|
30233688 |
2018 |
Diabetic Nephropathy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In view of the regulation of inflammation and fibrosis by myocardin-related transcription factor A (MRTF-A), we are highly concerned whether CK2α promotes AGEs-induced expressions of FN and ICAM-1 in glomerular mesangial cells via activation of MRTF-A, thus affecting the pathogenesis of DN.
|
29223351 |
2018 |
Diabetic Nephropathy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The expression of FN, Col‑I, SCF and c‑kit mRNA and protein was upregulated in the tubulointerstitium of DKD model rats compared with the normal control rats, and tranilast inhibited the upregulated expression of these markers.
|
29568954 |
2018 |
Malignant neoplasm of breast
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In addition, overexpression of wild-type p53 markedly decreased the level of FN expression in p53-mutant breast cancer cells.
|
28765903 |
2017 |