SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Heart Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018799
Disease: Heart Diseases
Heart Diseases 		0.330 Biomarker group BEFREE In conclusion, the results suggested that SAB could attenuate HUVEC cells damage treated with HG or PA via Sirt1 and might be a potential therapy agent for the diabetic cardiopathy treatment. 31118974 2019
CUI: C0018799
Disease: Heart Diseases
Heart Diseases 		0.330 Biomarker group BEFREE Sirtuin 1 (SirT1) is a protein deacetylase of the sirtuin family, whose activation appears beneficial for cardiac diseases. 22370592 2013
CUI: C0018799
Disease: Heart Diseases
Heart Diseases 		0.330 Biomarker group CTD_human Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria. 23217256 2012
CUI: C0018799
Disease: Heart Diseases
Heart Diseases 		0.330 Biomarker group BEFREE Recent evidence suggests that stimulation of Sirt1 mimics ischemic preconditioning and protects the heart from I/R injury, suggesting an intriguing possibility of using longevity factors to treat cardiac disease. 22498017 2011