SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Prostatic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.340 Biomarker group CTD_human Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model. 21062352 2011
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.340 AlteredExpression group LHGDN A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells. 18573234 2008
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.340 Biomarker group LHGDN Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor. 17505061 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.340 AlteredExpression group BEFREE Second, immunohistochemistry was done on human prostate tumors to determine if SIRT1 was differentially expressed in tumor cells versus uninvolved cells. 17638871 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.340 Biomarker group LHGDN Furthermore, immunostaining of human prostate tumors showed that cancer cells had greater SIRT1 expression than uninvolved cells. 17638871 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.340 AlteredExpression group LHGDN Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. 15692560 2005