ALK, ALK receptor tyrosine kinase, 238

N. diseases: 519; N. variants: 41
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.700 CausalMutation disease CGI
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder)
0.700 CausalMutation disease CGI
CUI: C0334121
Disease: Inflammatory Myofibroblastic Tumor
Inflammatory Myofibroblastic Tumor
0.700 CausalMutation disease CGI
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
0.610 CausalMutation group CGI
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.600 CausalMutation disease CGI
Ki-1+ Anaplastic Large Cell Lymphoma
0.600 CausalMutation disease CGI
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
0.600 GeneticVariation disease CLINVAR
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
0.600 CausalMutation disease CLINVAR
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
0.600 SusceptibilityMutation disease CLINVAR
CUI: C0035412
Disease: Rhabdomyosarcoma
Rhabdomyosarcoma
0.500 CausalMutation disease CGI
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
0.500 CausalMutation disease CGI
CUI: C3899155
Disease: hereditary neuroblastoma
hereditary neuroblastoma
0.400 Biomarker disease GENOMICS_ENGLAND
CUI: C0025202
Disease: melanoma
melanoma
0.390 CausalMutation disease CGI
CUI: C1333294
Disease: ALK positive large B-cell lymphoma
ALK positive large B-cell lymphoma
0.360 FusionGene disease ORPHANET
CUI: C0017638
Disease: Glioma
Glioma
0.320 CausalMutation disease CGI
CUI: C1335177
Disease: Ovarian Serous Adenocarcinoma
Ovarian Serous Adenocarcinoma
0.310 GeneticVariation disease UNIPROT
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
0.300 CausalMutation disease CGI
CUI: C0027766
Disease: Nervous System Neoplasms
Nervous System Neoplasms
0.100 Biomarker group HPO
CUI: C0241577
Disease: Elevated urinary catecholamines
Elevated urinary catecholamines
0.100 Biomarker phenotype HPO
CUI: C2749484
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO
NEUROBLASTOMA, SUSCEPTIBILITY TO
0.100 GeneticVariation phenotype CLINVAR Valproate-induced hepatoxicity: protective effect of L-carnitine supplementation. 2124297 1990
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE Unscheduled expression of the truncated ALK may contribute to malignant transformation in these lymphomas. 8122112 1994
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.100 Biomarker disease BEFREE Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. 8122112 1994
CUI: C0220605
Disease: Adult Non-Hodgkin Lymphoma
Adult Non-Hodgkin Lymphoma
0.100 Biomarker disease BEFREE Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. 8122112 1994
CUI: C0220612
Disease: Childhood Non-Hodgkin Lymphoma
Childhood Non-Hodgkin Lymphoma
0.100 Biomarker disease BEFREE Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. 8122112 1994
CUI: C4721532
Disease: Lymphoma, Non-Hodgkin, Familial
Lymphoma, Non-Hodgkin, Familial
0.100 Biomarker disease BEFREE Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. 8122112 1994