MTOR, mechanistic target of rapamycin kinase, 2475

N. diseases: 960; N. variants: 48
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 Biomarker group BEFREE Hypertension is a common side effect of mTORC1 (mammalian target of rapamycin complex 1) inhibitors. 31378107 2019
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 Biomarker group BEFREE In our cohort, the prevalence of arterial hypertension has increased up to 53% after LT, and metabolic comorbidities and immunosuppressive treatment with mammalian target of rapamycin inhibitors are the risk factors for the development of hypertension after LT. 29366595 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 AlteredExpression group BEFREE Thus, inappropriate regulation of renal mTOR has the potential to result in electrolyte disturbances, such as acidosis/alkalosis, hyponatremia, and hypertension. 29846113 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 Biomarker group BEFREE Inhibition of Mammalian Target of Rapamycin Complex 1 Attenuates Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive Rats. 28827472 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 Biomarker group RGD Activation of the Renal PI3K/Akt/mTOR Signaling Pathway in a DOCA-Salt Model of Hypertension. 23323219 2012
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 Biomarker group CTD_human Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1. 19289642 2009