BBC3, BCL2 binding component 3, 27113

N. diseases: 157; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.060 Biomarker group BEFREE Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis. 24763611 2014
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.060 Biomarker group LHGDN Sp1 is involved in H2O2-induced PUMA gene expression and apoptosis in colorectal cancer cells. 18811981 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.060 Biomarker group LHGDN The BH3-only protein PUMA is involved in green tea polyphenol-induced apoptosis in colorectal cancer cell lines. 18367875 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.060 AlteredExpression group LHGDN Pro-apoptotic PUMA and anti-apoptotic phospho-BAD are highly expressed in colorectal carcinomas. 17393317 2007
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.060 AlteredExpression group LHGDN mRNA and protein expression of PUMA in sporadic colorectal cancer. 15547745 2004
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.060 Biomarker group LHGDN PUMA mediates the apoptotic response to p53 in colorectal cancer cells. 12574499 2003