GMPR, guanosine monophosphate reductase, 2766

N. diseases: 18; N. variants: 27
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.020 Biomarker disease BEFREE Reciprocally, transactivation of GMPR is required for MITF-dependent suppression of melanoma cell invasion, tumorigenicity and lung colonization. 27181209 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.020 Biomarker disease BEFREE Our data identify GMPR as a melanoma invasion suppressor and establish a link between guanosine metabolism and Rho-GTPase-dependent melanoma cell invasion. 24139804 2013