|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
This study investigated the impact of oral treatment with Ang-(1-7) included in hydroxypropyl β-cyclodextrin (HPβCD/Ang-(1-7)) on the cardiac proteome dysregulation due to experimental myocardial infarction.
|
31437601 |
2019 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
We found in the Lin<sup>-</sup> group that several angiogenic trophic factors (vascular endothelial growth factor, Angiopoietin-1, basic fibroblast growth factor, platelet-derived growth factor-aa) plasma level significantly increased to the 4th day after myocardial infarction.
|
31284593 |
2019 |
|
Myocardial Infarction
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
The concentration of sTie2 is increased in a range of conditions, including peripheral arterial disease and myocardial infarction, where it has been suggested to bind and block Angpt1 resulting in vascular dysfunction.
|
28623351 |
2017 |
|
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Fifty MI dogs were randomly divided into 5 groups and transfected with Ang-1 gene plasmid: (i) group A: only injection of microbubbles and Ang-1 plasmid; (ii) group B: only UTMD mediated gene transfection; (iii) group C: UTMD combined with classical NLS mediated gene transfection; (iv) group D: UTMD combined with mutational NLS mediated transfection; and (v) group E: UTMD combined with classical NLS in the presence of a nucleus transport blocker.
|
29259991 |
2017 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
To investigate how ACE2‑Ang‑(1‑7)‑MasR axis function on myocardial remodeling and cardiac fibrosis in post‑myocardial infarction (MI), male Sprague‑Dawley rats (weight, 200±20 g) were used to establish the model of myocardial infarction by ligating the left coronary artery.
|
28656296 |
2017 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
Concentration-effect curves to Ang I and Ang II were performed in mesenteric resistance arteries from male wild type (WT) and ELA-2 knockout (ELA-2KO) mice subjected to left anterior descending coronary artery ligation (MI).
|
28222221 |
2017 |
|
Myocardial Infarction
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
Western blot analysis showed increased VEGF, Ang-1 & Bcl-2 expression in PHD3⁻/⁻MI group.
|
23978105 |
2014 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
A nanobiohybrid complex of recombinant baculovirus and Tat/DNA nanoparticles for delivery of Ang-1 transgene in myocardial infarction therapy.
|
21840594 |
2011 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
Ad*VEGF and Ad*Ang1 were intramyocardially administered in combination immediately after myocardial infarction to nondiabetic and diabetic rats.
|
19794062 |
2010 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
We compare the effectiveness of direct adenoviral angiopoietin-1 (Ad-Ang-1) injection with transplantation of skeletal myoblasts (SkMs) over-expressing angiopoietin-1 (Ang-1) for angiogenic response and improvement of heart function in an experimental porcine model of myocardial infarction (MI).
|
17188570 |
2007 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
The results showed positive effect of VEGF(165), Ang1 and VEGF(165)+Ang1 on decreasing the myocardial infarct size at the 7th day.
|
15510173 |
2005 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
RGD |
Thus, myocardial ischemia induced by left coronary artery ligation resulted in a sustained increase in Ang-2 expression and a reciprocal decrease in Ang-1, consistent with a predominant role for Ang-2 in the angiogenic response to MI.
|
15364619 |
2004 |