Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 Biomarker group BEFREE Among the 19 NP syndromes, serum/plasma anti-NR2A/B antibodies were not specifically associated with any NP syndrome, including cognitive dysfunction (p=0.259) and mood disorder (p=0.503). 27988431 2017
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 Biomarker group PSYGENET To further investigate the contribution of the GluN2A-containing NMDA receptors in mood disorders we analysed mice lacking the intracellular C-terminus of the GluN2A subunit (GluN2AΔC/ΔC) in tests relevant for anxiety and depression. 23557693 2013
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 Biomarker group PSYGENET In the present study, we used in situ hybridization to measure the expression of NMDA subunits (NR1, NR2A-D), and associated intracellular proteins (NF-L, PSD95, and SAP102) in a second, younger cohort from the Stanley Foundation Neuropathology Consortium, which included patients with both schizophrenia and affective disorders. 15054476 2004
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 GeneticVariation group BEFREE In the present study, we used in situ hybridization to measure the expression of NMDA subunits (NR1, NR2A-D), and associated intracellular proteins (NF-L, PSD95, and SAP102) in a second, younger cohort from the Stanley Foundation Neuropathology Consortium, which included patients with both schizophrenia and affective disorders. 15054476 2004
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 Biomarker group PSYGENET We examined the role of the N-methyl-D-aspartate receptor 2A subunit (GRIN2A) gene on 16p13.3, a region thought to be linked to bipolar disorder, (1) because in a prior study we identified a functional and polymorphic (GT)n repeat in the 5' regulatory region of the gene, with longer alleles showing lower transcriptional activity and an over representation in schizophrenia, and (2) because of the suggestion of a genetic overlap between affective disorder and schizophrenia. 12809987 2003
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 GeneticVariation group BEFREE We examined the role of the N-methyl-D-aspartate receptor 2A subunit (GRIN2A) gene on 16p13.3, a region thought to be linked to bipolar disorder, (1) because in a prior study we identified a functional and polymorphic (GT)n repeat in the 5' regulatory region of the gene, with longer alleles showing lower transcriptional activity and an over representation in schizophrenia, and (2) because of the suggestion of a genetic overlap between affective disorder and schizophrenia. 12809987 2003