Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0431380
Disease: Cortical Dysplasia
Cortical Dysplasia
0.020 AlteredExpression disease BEFREE NR2B upregulation in cortical dysplasia was greater in the total homogenate than the postsynaptic membrane fraction, suggesting that mechanisms other than increased ionic influx through the postsynaptic membrane may sustain hyperexcitability in dysplastic neurons. 16957582 2006
CUI: C0431380
Disease: Cortical Dysplasia
Cortical Dysplasia
0.020 AlteredExpression disease BEFREE These results suggest that increased coassembly of NR2B and NR1 with PSD-95 may underlie one of the cellular mechanisms that contribute to the in situ increased hyperexcitability, leading to seizure generation in focal CD. 15030493 2004