GSK3B, glycogen synthase kinase 3 beta, 2932

N. diseases: 393; N. variants: 25
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 GeneticVariation group BEFREE An increasing amount of preclinical and clinical evidence links together metabolic regulations and psychopathological mechanisms, in particular linking mood disorders with changes in Glycogen Synthase Kinase 3 beta and 5'Adenosine Monophosphate-activated Protein Kinase expression and activity. 31153593 2019
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 Biomarker group BEFREE And it should be further studied whether the GSK3B-insomnia association may fit into the larger picture of mood disorders. 30081294 2018
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 Biomarker group BEFREE Glycogen synthase kinase 3β (GSK3β) has been implicated in mood disorders. 30080747 2018
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 Biomarker group BEFREE We then highlight evidence suggesting that GSK3β influences hippocampal volume in MDD patients, and how this could assist with targeting more precise treatments particularly for cognitive deficits in patients with mood disorders. 30310078 2018
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 GeneticVariation group BEFREE The interaction of GSK3B and FXR1 genotypes may influence the mania and depression dimensions in mood disorders. 28242499 2017
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 Biomarker group PSYGENET A haplotype of glycogen synthase kinase 3β is associated with early onset of unipolar major depression. 20618448 2010
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 GeneticVariation group BEFREE We hypothesized that genetic variants in the GSK3β gene could partially underlie the susceptibility to mood disorders. 20618448 2010
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 Biomarker group PSYGENET Several lines of evidence implicate glycogen synthase kinase 3 beta (GSK3beta) in mood disorders. 20219685 2010
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 Biomarker group BEFREE Several lines of evidence implicate glycogen synthase kinase 3 beta (GSK3beta) in mood disorders. 20219685 2010
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.380 GeneticVariation group LHGDN Association between GSK-3beta -50T/C polymorphism and personality and psychotic symptoms in mood disorders. 17976739 2008