Glioma
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, the meta-analysis suggests that there is no association between GSTP1 Ile105Val polymorphism and glioma risk.
|
23975366 |
2014 |
Glioma
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
There was evidence of supermultiplicativity of the joint effect of GSTP1 I105V and CYP2E1 RsaI variants on both glioma and acoustic neuroma, even following adjustment of estimates toward a common prior distribution using hierarchical regression models.
|
12540498 |
2003 |
Glioma
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
We identified two tSNPs to be associated with glioma susceptibility (rs1695, GSTP1, P = 0.019; rs2853676, TERT, P = 0.039), which we confirmed using dominant and additive model analyses.
|
22795327 |
2012 |
Glioma
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
The combined results based on all studies showed that there was no association between any of the GST variants and the risk of glioma (for GSTM1: pooled OR = 1.03; 95 % CI, 0.92-1.15; for GSTT1: pooled OR = 1.12; 95 % CI, 0.90-1.40; for GSTP1 I105V: pooled OR = 0.92; 95 % CI, 0.64-1.31 and for GSTP1 A114V: pooled OR = 1.14; 95 % CI, 0.97-1.34).
|
23079710 |
2013 |
Glioma
|
0.380 |
Biomarker
|
disease |
CTD_human |
In vitro drug response and molecular markers associated with drug resistance in malignant gliomas.
|
16899598 |
2006 |
Glioma
|
0.380 |
Biomarker
|
disease |
BEFREE |
We found no associations between the GSTM3, GSTP1, NQO1, CYP1A1, GSTM1, or GSTT1 polymorphisms and adult brain tumor risk with the possible exception of a weak association between the G-C (Val-Ala) GSTP1 105/114 haplotype and glioma [odds ratio (OR), 0.73; 95% confidence interval (95% CI), 0.54, 0.99], nor was there an interaction between the effects of the GSTM3 or GSTP1 polymorphisms and cigarette smoking.
|
17372252 |
2007 |
Glioma
|
0.380 |
Biomarker
|
disease |
BEFREE |
Polymorphisms in GSTM1, GSTT1, and GSTP1 did not show association with histopathologic type of brain tumor (glioma or meningioma).
|
15642394 |
2005 |
Glioma
|
0.380 |
Biomarker
|
disease |
BEFREE |
No significant differences in gene and protein expression were detected between the different types of gliomas, suggesting that glioma chemoresistance is probably multifactorial and GSTP1-independent.
|
30952719 |
2019 |
Glioma
|
0.380 |
Biomarker
|
disease |
BEFREE |
The effects of the changes in MTase levels on global genomic DNA methylation and on the methylation status of CpG dinucleotides in the GSTP1 gene were determined in a glioma cell line that overexpresses the GSTP1 gene.
|
10760946 |
2000 |