GSTP1, glutathione S-transferase pi 1, 2950

N. diseases: 610; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 Biomarker disease BEFREE Genetic polymorphisms of glutathione S-transferases GSTM1, GSTT1, GSTP1 and GSTA1 as risk factors for schizophrenia. 21093063 2011
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 Biomarker disease BEFREE In the present study, the relationship between TD and a functional polymorphism of the gene coding for human glutathione S-transferase P1 (GSTP1), an important antioxidant enzyme involved in the detoxification of ROS, was studied in 225 chronic treatment-refractory patients with schizophrenia. 16039055 2005
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 GeneticVariation disease BEFREE Our meta-analysis results revealed that GSTM1, GSTT1, and GSTP1 polymorphisms were not related to risk of schizophrenia (p > 0.05 in each model). 26295386 2015
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 GeneticVariation disease BEFREE Our results suggest that GPX1 rs1050450 and GSTP1 rs1695 SNPs are unlikely to play a major role in the pathogenesis of schizophrenia in the Chinese Han population. 28872562 2017
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 GeneticVariation disease BEFREE The present study suggests that GSTP1 polymorphism may not confer susceptibility to development of schizophrenia in the Korean population. 12691788 2003
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 Biomarker disease PSYGENET The present study suggests that GSTP1 polymorphism may not confer susceptibility to development of schizophrenia in the Korean population. 12691788 2003
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 Biomarker disease PSYGENET The present study supports the hypothesis that impairment in the promoter region of GSTT and GSTP genes by hypermethylation may increase the risk of schizophrenia. 25358668 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 PosttranslationalModification disease BEFREE The present study supports the hypothesis that impairment in the promoter region of GSTT and GSTP genes by hypermethylation may increase the risk of schizophrenia. 25358668 2014