Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.390 GeneticVariation disease BEFREE Association between GSTP1 Ile105Val polymorphism and glioma risk: a systematic review and meta-analysis. 23975366 2014
CUI: C0017638
Disease: Glioma
Glioma
0.390 GeneticVariation disease BEFREE However, the significant risk elevation is present between GSTP1 A114V genotype and other histopathologic glioma except GBM. 23079710 2013
CUI: C0017638
Disease: Glioma
Glioma
0.390 GeneticVariation disease BEFREE Selected polymorphisms of GSTP1 and TERT were associated with glioma risk in Han Chinese. 22795327 2013
CUI: C0017638
Disease: Glioma
Glioma
0.390 Biomarker disease BEFREE Serine phosphorylation of glutathione S-transferase P1 (GSTP1) by PKCα enhances GSTP1-dependent cisplatin metabolism and resistance in human glioma cells. 20654585 2010
CUI: C0017638
Disease: Glioma
Glioma
0.390 Biomarker disease BEFREE Mass spectrometry and mutagenesis analyses in a cell-free system and in gliomas cells identified Tyr-7 and Tyr-198 as major EGFR-specific phospho-acceptor residues in the GSTP1 protein. 19254954 2009
CUI: C0017638
Disease: Glioma
Glioma
0.390 GeneticVariation disease BEFREE We found no associations between the GSTM3, GSTP1, NQO1, CYP1A1, GSTM1, or GSTT1 polymorphisms and adult brain tumor risk with the possible exception of a weak association between the G-C (Val-Ala) GSTP1 105/114 haplotype and glioma [odds ratio (OR), 0.73; 95% confidence interval (95% CI), 0.54, 0.99], nor was there an interaction between the effects of the GSTM3 or GSTP1 polymorphisms and cigarette smoking. 17372252 2007
CUI: C0017638
Disease: Glioma
Glioma
0.390 Biomarker disease CTD_human In vitro drug response and molecular markers associated with drug resistance in malignant gliomas. 16899598 2007
CUI: C0017638
Disease: Glioma
Glioma
0.390 Biomarker disease BEFREE Polymorphisms in GSTM1, GSTT1, and GSTP1 did not show association with histopathologic type of brain tumor (glioma or meningioma). 15642394 2005
CUI: C0017638
Disease: Glioma
Glioma
0.390 GeneticVariation disease BEFREE There was evidence of supermultiplicativity of the joint effect of GSTP1 I105V and CYP2E1 RsaI variants on both glioma and acoustic neuroma, even following adjustment of estimates toward a common prior distribution using hierarchical regression models. 12540498 2003
CUI: C0017638
Disease: Glioma
Glioma
0.390 GeneticVariation disease BEFREE DNA methyltransferase levels and altered CpG methylation in the total genome and in the GSTP1 gene in human glioma cells transfected with sense and antisense DNA methyltransferase cDNA. 10760946 2000