Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Histone deacetylase 1/Sp1/microRNA-200b signaling accounts for maintenance of cancer stem-like cells in human lung adenocarcinoma.
|
25279705 |
2014 |
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Histone deacetylase 1/Sp1/microRNA-200b signaling accounts for maintenance of cancer stem-like cells in human lung adenocarcinoma.
|
25279705 |
2014 |
Adenocarcinoma of lung (disorder)
|
0.040 |
Biomarker
|
disease |
BEFREE |
Histone deacetylase 1/Sp1/microRNA-200b signaling accounts for maintenance of cancer stem-like cells in human lung adenocarcinoma.
|
25279705 |
2014 |
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
HDAC1 inhibition-induced DUSP1 upregulation could be a promising strategy to overcome gefitinib-acquired resistance.Clin Cancer Res; 21(2); 428-38.©2015 AACR.
|
25593344 |
2015 |
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
HDAC1 inhibition-induced DUSP1 upregulation could be a promising strategy to overcome gefitinib-acquired resistance.Clin Cancer Res; 21(2); 428-38.©2015 AACR.
|
25593344 |
2015 |
Fibrosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Histone deacetylase 1 and histone 3 were more strongly detected in hepatocellular carcinoma tissue and fibrosarcoma cells than in liver tissues and fibroblast cells, respectively.
|
25792651 |
2015 |
Adult Fibrosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Histone deacetylase 1 and histone 3 were more strongly detected in hepatocellular carcinoma tissue and fibrosarcoma cells than in liver tissues and fibroblast cells, respectively.
|
25792651 |
2015 |
Liver carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Histone deacetylase 1 overexpression and hypoacetylation of histone 3 might play critical roles in the modulation of histone 3 in human hepatocellular carcinoma.
|
25792651 |
2015 |
Malignant neoplasm of prostate
|
0.100 |
Biomarker
|
disease |
BEFREE |
HDAC1 has strong prognostic impact in prostate cancer and might contribute to the development of a fraction of genetically instable and particularly aggressive prostate cancers.
|
25794974 |
2015 |
Prostate carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
HDAC1 has strong prognostic impact in prostate cancer and might contribute to the development of a fraction of genetically instable and particularly aggressive prostate cancers.
|
25794974 |
2015 |
Tumor Cell Invasion
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
HDAC1(KD) resulted in reduced proliferation, invasion and migration in vitro and transcriptome profiling revealed effects on expression of genes regulating proliferation migration and inflammation.
|
26152200 |
2015 |
Carcinogenesis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Hdac1 and Hdac2 promote tumorigenesis in a gene dose-dependent manner, with a predominant function of Hdac1.
|
27886239 |
2016 |
Actinic cheilitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
HDAC1 and HAT1 nuclear immunostaining were higher in AC, with no statistical significance.
|
28107582 |
2017 |
Tuberculosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
HDAC1 gene/protein expressions were increased in TB patients as compared with that in HS, whereas KDM6B gene/protein expressions were decreased.
|
28469799 |
2017 |
Stress, Psychological
|
0.010 |
Biomarker
|
disease |
BEFREE |
HDAC1 links early life stress to schizophrenia-like phenotypes.
|
28533418 |
2017 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.
|
28579617 |
2018 |
leukemia
|
0.030 |
Biomarker
|
disease |
BEFREE |
HDAC1,2 inhibitor either alone or when combined with doxorubicin decreases leukemia burden in vivo in refractory Ph+ B-cell precursor ALL patient-derived xenograft mouse models.
|
28579617 |
2018 |
Childhood Leukemia
|
0.030 |
Biomarker
|
disease |
BEFREE |
HDAC1,2 inhibitor either alone or when combined with doxorubicin decreases leukemia burden in vivo in refractory Ph+ B-cell precursor ALL patient-derived xenograft mouse models.
|
28579617 |
2018 |
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Histone deacetylase 1 (HDAC1) is an important epigenetic factor, and is thought to be associated with the progression and prognosis of some types of cancer.
|
28767587 |
2017 |
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Histone deacetylase 1 (HDAC1) is an important epigenetic factor, and is thought to be associated with the progression and prognosis of some types of cancer.
|
28767587 |
2017 |
Influenza A
|
0.020 |
Biomarker
|
disease |
BEFREE |
Histone Deacetylase 1 Plays an Acetylation-Independent Role in Influenza A Virus Replication.
|
29312300 |
2017 |
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
HDAC1 dysfunction has been implicated in cancer development and progression; thus, its inhibition has emerged as a new therapeutic strategy.
|
29447615 |
2019 |
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
HDAC1 dysfunction has been implicated in cancer development and progression; thus, its inhibition has emerged as a new therapeutic strategy.
|
29447615 |
2019 |
Cystadenocarcinoma, Serous
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
HDAC1 nuclear expression adversely affected overall survival in SEC (P=0.02) and EMC (P=0.03), and HDAC7 cytoplasmic expression in CCC was associated with a poor prognosis (P=0.06).
|
29456726 |
2018 |
Extraskeletal Myxoid Chondrosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
HDAC1 nuclear expression adversely affected overall survival in SEC (P=0.02) and EMC (P=0.03), and HDAC7 cytoplasmic expression in CCC was associated with a poor prognosis (P=0.06).
|
29456726 |
2018 |