HDGF, heparin binding growth factor, 3068

N. diseases: 89; N. variants: 1
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE Hepatoma-derived growth factor (HDGF) has been considered as a potential glioma therapeutic target, and its expression level in gliomas is positively related to the malignant grade. 31404556 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.050 AlteredExpression disease BEFREE In summary, this study demonstrated that AGAP2-AS1 promoted glioma cell proliferation by sponging miR-15a/b-5p to upregulate the expression of HDGF. 30684575 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.050 AlteredExpression disease BEFREE Overall, HDGF upregulation may be a crucial step in the development and invasion of glioma. 29344149 2017
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE A complex mechanism for HDGF-mediated cell growth, migration, invasion, and TMZ chemosensitivity in glioma. 24986090 2014
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE We conclude that HDGF is a mitogenic growth factor in glioma progression and can be a useful prognostic marker for GBM and therapeutic target for clinical management of glioma in the future. 22037800 2012