HDGF, heparin binding growth factor, 3068

N. diseases: 89; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 AlteredExpression phenotype BEFREE Dysregulation of HDGF expression during cancer development and tumor progression is a commonly known fact. 27926477 2017
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 AlteredExpression phenotype BEFREE Our previous study demonstrated that high expression levels of HDGF in hilar cholangiocarcinoma tissues correlates with tumor progression and patient outcome. 26081074 2015
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 Biomarker phenotype BEFREE This review is focused on the role of HDGF in tumorigenesis and metastasis, and provides insight for application in clinical cancer therapy as well as its clinical implications as a prognostic marker in cancer progression. 25236340 2014
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 Biomarker phenotype BEFREE The present study provides evidence that HDGF promotes tumor progression of melanoma and targeting HDGF may constitute a novel strategy for the treatment of melanoma. 23536873 2013
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.050 Biomarker phenotype BEFREE In various malignant tumors, the role of HDGF in tumor progression and its use as a diagnostic biomarker or therapeutic target have been extensively explored. 22037800 2012