CD209, CD209 molecule, 30835

N. diseases: 57; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.050 GeneticVariation disease BEFREE <i>Conclusions</i>: Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (<i>DC-SIGN</i>) promoter-336G/A (<i>rs4804803</i>) polymorphism is association with severe dengue, and it acts in different directions for Asians and South-central Americans. 31027310 2019
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.050 GeneticVariation disease BEFREE A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF). 29054571 2018
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.050 GeneticVariation disease BEFREE We demonstrated that the TT genotype of CLEC5A SNP (rs1285933 C>T) is associated with dengue severity (OR=2.25; p=0.03) and that GG genotype of -336G>A DCSIGN (CD209) SNP is associated with protection to severe dengue (OR=0.12; p=0.04). 24016730 2013
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.050 GeneticVariation disease BEFREE the rs4804803 SNP in the CD209 promoter contributed to susceptibility to dengue infection and complication of DHF. 21245921 2011
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.050 Biomarker disease BEFREE These results indicate that CD209 has a crucial role in dengue pathogenesis, which discriminates between severe dengue fever and dengue hemorrhagic fever. 15838506 2005