|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Frequencies of HLA-DQB1 alleles and phenotype in RA patients and healthy controls.
|
28455285 |
2017 |
|
Rheumatoid Arthritis
|
0.200 |
PosttranslationalModification
|
disease |
BEFREE |
In addition, the result showed that human leukocyte antigen (HLA) region including HLA-DRB6, HLA-DQA1 and HLA-E was frequently hypomethylated, but HLA-DQB1 hypermethylated in CpG island region and hypomethylated in CpG shelf region in RA patients.
|
27585642 |
2017 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
In this context, we studied the HLA-DRB1 and HLA-DQB1 first-level allele frequencies in 100 Albanian patients with rheumatoid arthritis (RA), and taking into account their rheumatoid factor (RF) and anticitrullinated peptide antibodies (ACPA) serologic subgroups, we compared them with the respective frequencies in a population of 191 Albanian individuals without known pathology.
|
24381092 |
2014 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The objective of this study was to examine HLA-DRB1 and HLA-DQB1 genotypes in patients with severe extra-articular rheumatoid arthritis (ExRA) and to compare them with the genotypes of rheumatoid arthritis (RA) patients without extra-articular manifestations.
|
16277691 |
2005 |
|
Rheumatoid Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
In contrast, the expression of MHC class II, DQ beta1 (HLA-DQB1) was significantly reduced in RA patients compared to healthy controls.
|
15158620 |
2004 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The role of HLA-DRB1*04 alleles and their association with HLA-DQB genes in genetic susceptibility to rheumatoid arthritis in Hungarian patients.
|
12793199 |
2003 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
LHGDN |
The role of HLA-DRB1*04 alleles and their association with HLA-DQB genes in genetic susceptibility to rheumatoid arthritis in Hungarian patients.
|
12793199 |
2003 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
No HLA-DRB1 independent association of the HLA-DQB1 alleles, implicated in predisposing to RA, was evident.
|
12233873 |
2002 |
|
Rheumatoid Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Our results show that HLA-DQB1*03/DQA1*03 (or DRB1*04) predisposes to RA more than HLA-DQB1*0501/DQA1*01 (i.e., DRB1*01 and DRB1*10).
|
11334677 |
2001 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Tumour necrosis factor microsatellites and HLA-DRB1*, HLA-DQA1*, and HLA-DQB1* alleles in Peruvian patients with rheumatoid arthritis.
|
11454644 |
2001 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
An endogenous retroviral long terminal repeat at the HLA-DQB1 gene locus confers susceptibility to rheumatoid arthritis.
|
9952028 |
1999 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
HLA-DQB1 polymorphism determines incidence, onset, and severity of collagen-induced arthritis in transgenic mice. Implications in human rheumatoid arthritis.
|
9410900 |
1997 |