Disease: IGA Glomerulonephritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.360 Biomarker disease BEFREE High frequency of HLA-DQB1* 060101 and low frequency of HLA-DQB1*030101 were observed in IgAN patients compared with healthy controls. 27896619 2016
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.360 Biomarker disease CTD_human Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens. 25305756 2014
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.360 GeneticVariation disease BEFREE In a recent GWAS, we localized five IgAN susceptibility loci on Chr.6p21 (HLA-DQB1/DRB1, PSMB9/TAP1, and DPA1/DPB2 loci), Chr.1q32 (CFHR3/R1 locus), and Chr.22q12 (HORMAD2 locus). 22737082 2012
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.360 Biomarker disease BEFREE Genes controlling the immune response, such as HLA DQB1 and the alpha1 transcriptional enhancer gene, may influence the development and/or the progression of IgA-N nephropathy. 12005241 2002
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.360 Biomarker disease BEFREE But the main result of our study is the identification of a strong association between HLA DQB1*0301 and IgAN patients with an unfavorable outcome. 7638860 1995
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.360 Biomarker disease BEFREE Candidate disease susceptibility genes include those encoding the MHC class II antigens, HLA-DR, -DQ, and -DP, and we have recently described an HLA-DQB1 association in IgAN. 1314989 1992
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.360 GeneticVariation disease BEFREE The DQw7 allele at the HLA-DQB locus is associated with susceptibility to IgA nephropathy in Caucasians. 1676769 1991