Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.180 GeneticVariation disease BEFREE Eight single-nucleotide polymorphisms in the proximity of HLA-DQB1 were associated with HCC (P < 8.7 × 10<sup>-8</sup> ) in the genome-wide association study. 28921602 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.180 GeneticVariation disease BEFREE The AG/GG genotype of rs9275572 and HLA-DQB1 Block2 CCCCC haplotype may have protective effects in HBV-related HCC patients receiving hepatic resection. 27288300 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.180 Biomarker disease BEFREE In addition, the decreased mRNA expression of STAT4, HLA-DQA1, and HLA-DQB1 in HCC tissue might provide a clue to understanding their role in the progression to HCC. 25913043 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.180 GeneticVariation disease BEFREE We suggest that alleles HLA-DRB 08, HLA-DRB 03 and HLA-DQB1 04 may be risk factors for hepatocellular carcinoma in Amazon. 23661457 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.180 GeneticVariation disease GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.180 GeneticVariation disease BEFREE The odds ratios (ORs) of HLA-DQB1 allele distributions in HCC patients were analyzed and compared with healthy controls. 21633537 2011
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.180 GeneticVariation disease LHGDN HLA-class II alleles in Egyptian patients with hepatocellular carcinoma. 18821214 2008
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.180 GeneticVariation disease BEFREE DNA obtained from 141 Spanish patients with HCV infection (48 with alanine aminotransferase levels in the range considered to be normal, 47 with liver cirrhosis, and 46 with hepatocellular carcinomas [HCCs]) and from 116 control subjects were typed for HLA-B, HLA-DRB1, and HLA-DQB1 alleles, as well as for major histocompatibility complex class I chain-related gene A (MICA) transmembrane polymorphism. 14999597 2004
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.180 GeneticVariation disease LHGDN Hepatitis C virus-related hepatocellular carcinoma and B-cell lymphoma patients show a different profile of major histocompatibility complex class II alleles. 15556690 2004