cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Protective associations between HLA-DRB1*13:02, HLA-DRB1*04:06, and HLA-DQB1*06:04 alleles and cervical cancer were found in the Korean population.
|
30352277 |
2019 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These findings supported that the HLA-DQB1 alleles may contribute to genetic susceptibility of cervical cancer.
|
26211583 |
2015 |
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
HLA-DQB1*0325 and HLA-DQB1*0332 probably act as cervical cancer susceptibility genes in Uyghur women from Xinjiang.
|
26681219 |
2015 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Thus, our data suggest that persistent HPV16/18 infection in the cervix due to the presence of the HLA-DQB1 A-allele and chronic inflammation due to the presence of the IL-1β -511 T-allele might predispose women to CaCx development.
|
25893807 |
2015 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
MHC loci affecting cervical cancer risk: distinguishing the effects of HLA-DQB1 and non-HLA genes TNF, LTA, TAP1 and TAP2.
|
18650831 |
2008 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
HLA-DQB1 polymorphisms and risk for cervical cancer: a case-control study in a southern Chinese population.
|
17379283 |
2007 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
HLA-DQB1*03 homozygosity (OR(age-adjusted) = 4.75; 95% CI: 1.17-19.30; P = 0.03) or p53Pro72Pro (OR(age-adjusted) = 5.84; 95% CI: 1.18-28.99; P = 0.03) was found to be significantly associated with CaCx, each in the absence of the other in this group but not when present jointly in contrast to those lacking both factors (P = 0.214).
|
17767549 |
2007 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This finding implies that polymorphic amino acids at the putative antigen binding residues 9 and 37 of HLA-DQB1 alleles may play an important role in the development of cervical cancer.
|
16425277 |
2006 |
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
We aimed to investigate the relationship between HLA-DQB1, HPV infection, and cervical cancer in Venezuelan women.
|
15661220 |
2005 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Epidemiological studies have demonstrated an association between HLA-DQB1*03 alleles and the risk of cervical cancer induced by human papillomavirus (HPV).
|
15257408 |
2004 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Furthermore, specific HLA-DQB1 sequences may be important in determining the immune response to HPV peptides and may affect the risk for cervical cancer after HPV infection in mestizo Honduran women.
|
10380373 |
1999 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Recently, it was demonstrated that there is a high risk for cervical cancer and CIN in women with HLA DQB1 * 03 (RR = 7.1, p < 0.0009) (1).
|
8529095 |
1995 |
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association between HLA-DQB1 alleles and risk for cervical cancer in African-American women.
|
8181853 |
1994 |