Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1258104
Disease: Diffuse Scleroderma
Diffuse Scleroderma
0.350 GeneticVariation disease BEFREE Furthermore, FLEDR is always carried by the most abundantly expressed ß chain: ß1 in HLA DRB1*11 haplotypes and ß5 in HLA-DRB1*15 haplotypes.In French Caucasian patients with SSc, FLEDR is the main presenting motif influencing ATA production in dcSSc. 22615829 2013
CUI: C1258104
Disease: Diffuse Scleroderma
Diffuse Scleroderma
0.350 Biomarker disease BEFREE Association analysis among TAP1A, TAP2A and DRB1*1502 indicated that increases in TAP1A and TAP2A were not primary, but were reflective of an increase in HLA DRB1*1502 in Japanese SSc patients with diffuse scleroderma and SSc with a-Scl-70. 8913653 1997
CUI: C1258104
Disease: Diffuse Scleroderma
Diffuse Scleroderma
0.350 Biomarker disease BEFREE Association analysis among DMA, DMB, and DRB1*1502 in Japanese SSc with diffuse scleroderma and SSc with a-Scl-70 indicated that the increase in DMA*0101 was not primary, but reflected an increase in HLA DRB1*1502. 9225871 1997
CUI: C1258104
Disease: Diffuse Scleroderma
Diffuse Scleroderma
0.350 AlteredExpression disease BEFREE Thus, 81.3% of a-Scl-70 positive patients, and 93.8% of patients with PSS with diffuse scleroderma showed either HLA-DRB1*1502 or 0802. 8064726 1994
CUI: C1258104
Disease: Diffuse Scleroderma
Diffuse Scleroderma
0.350 Biomarker disease BEFREE DNA-DR typing shows HLA-DRw11 RFLPs are increased in frequency in both progressive systemic sclerosis and CREST variants of scleroderma. 2568026 1989
CUI: C1258104
Disease: Diffuse Scleroderma
Diffuse Scleroderma
0.350 SusceptibilityMutation disease ORPHANET