Disease: Down Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker disease BEFREE Herein, we examine the expression of four dosage-sensitive genes (APP, ETS2, SOD1, and HMGN1) in normal and DS placentas. 30031727 2018
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 AlteredExpression disease BEFREE High mobility group N1 protein (HMGN1), a nucleosomal-binding protein that affects the structure and function of chromatin, is encoded by a gene located on chromosome 21 and is overexpressed in Down syndrome, one of the most prevalent genomic disorders. 22009741 2011
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 AlteredExpression disease BEFREE The putative role of HMG-14 in the structure of active chromatin raises the possibility that elevated levels of this protein may be a contributing factor in the etiology of Down syndrome. 1825298 1991
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker disease BEFREE The HMG-14 gene may be an additional marker for the Down syndrome. 2140193 1990