HMOX1, heme oxygenase 1, 3162

N. diseases: 666; N. variants: 9
Disease: Inflammation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021368
Disease: Inflammation
Inflammation 		0.350 Biomarker phenotype CTD_human We show for the first time that Hmox1 is constitutively expressed at barrier tissues at the interface between the internal and external environments, and that it is highly induced in muscle cells during systemic inflammation. 29086419 2018
CUI: C0021368
Disease: Inflammation
Inflammation 		0.350 Biomarker phenotype CTD_human Milano summer particulate matter (PM10) triggers lung inflammation and extra pulmonary adverse events in mice. 23451061 2013
CUI: C0021368
Disease: Inflammation
Inflammation 		0.350 Biomarker phenotype LHGDN Cigarette smoke-induced expression of heme oxygenase-1 in human lung fibroblasts is regulated by intracellular glutathione. 18689604 2008
CUI: C0021368
Disease: Inflammation
Inflammation 		0.350 AlteredExpression phenotype LHGDN Higher levels of Hsp32, Hsp70 and Hsp90 were noticed in patients with inflammation, a commonly occurring natural stimulant of Hsp production, compared to control subjects. 17211576 2007
CUI: C0021368
Disease: Inflammation
Inflammation 		0.350 AlteredExpression phenotype LHGDN Heme oxygenase (HO)-1 is upregulated in the nasal mucosa with allergic rhinitis. 16540907 2006
CUI: C0021368
Disease: Inflammation
Inflammation 		0.350 Biomarker phenotype CTD_human Basal rather than induced heme oxygenase-1 levels are crucial in the antioxidant cytoprotection. 16982915 2006
CUI: C0021368
Disease: Inflammation
Inflammation 		0.350 Biomarker phenotype LHGDN These results demonstrate that HO-1 activity operates through distinct molecular mechanisms to confer cytoprotection in the hypoxic and the LPS models of inflammation. 12709566 2003
CUI: C0021368
Disease: Inflammation
Inflammation 		0.350 AlteredExpression phenotype LHGDN The heme-heme oxygenase system: a molecular switch in wound healing. 12649161 2003
CUI: C0021368
Disease: Inflammation
Inflammation 		0.350 Biomarker phenotype CTD_human The heme-heme oxygenase system: a molecular switch in wound healing. 12649161 2003