HMOX1, heme oxygenase 1, 3162

N. diseases: 666; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0034067
Disease: Pulmonary Emphysema
Pulmonary Emphysema
0.330 AlteredExpression disease BEFREE Tobacco may be involved in the decreased macrophage heme oxygenase-1 (HO-1) expression described in smoking-induced severe emphysema, via the nuclear factor erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1)-BTB and CNC homology 1, basic leucine zipper transcription factor 1 (Bach1) pathway. 19822148 2009
CUI: C0034067
Disease: Pulmonary Emphysema
Pulmonary Emphysema
0.330 GeneticVariation disease BEFREE Polymorphism in the HO-1 gene promoter was shown to be associated with susceptibility to pulmonary emphysema and restenosis after angioplasty. 12730098 2003
CUI: C0034067
Disease: Pulmonary Emphysema
Pulmonary Emphysema
0.330 Biomarker disease CTD_human Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. 10631150 2000
CUI: C0034067
Disease: Pulmonary Emphysema
Pulmonary Emphysema
0.330 GeneticVariation disease BEFREE Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. 10631150 2000