FOXA1, forkhead box A1, 3169

N. diseases: 138; N. variants: 1
Disease: Esophageal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.040 Biomarker group BEFREE Members of the forkhead-box A (FOXA) family, including FOXA1 and FOXA2, have been reported to regulate EC progression. 30944629 2019
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.040 GeneticVariation group BEFREE Forkhead box A1 (FOXA1) tagging polymorphisms and esophageal cancer risk in a Chinese population: a fine-mapping study. 27050876 2016
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.040 AlteredExpression group BEFREE It was also revealed that FOXA1 siRNA treatment of esophageal cancer cells reduced the mRNA level of both KRT7 and a stabilizer of epithelial-mesenchymal transition (EMT) regulator LOXL2, and that both FOXA1 and LOXL2 siRNAs reduced invasion and migration of ESCC cells. 20043065 2010
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.040 Biomarker group BEFREE Quantitative reverse transcription-PCR (RT-PCR) of 8 genes and expressed sequence tags located within the core-amplified domain revealed that the HNF3alpha (FOXA1)(4) gene, a forkhead gene family member, was overexpressed in all of the amplified esophageal tumors. 12234996 2002